Journal: Micromachines

Article Title: The Emerging Frontiers and Applications of High-Resolution 3D Printing

doi: 10.3390/mi8040113

Figure Lengend Snippet: ( A ) 3D printed Polycaprolactone (PCL) scaffold with fibers spacing 0.2 mm; ( B ) 3D printed PCL scaffold with fibers spacing 1.0 mm; ( C ) detailed image of scaffold with fibers spacing 1.0 mm; ( D ) hydrogel without PCL scaffold; ( E ) hydrogel reinforced with a PCL scaffold; and ( F ) DAPI staining demonstrated the homogenous distribution of the cells throughout the construct; ( A – F ) are reprinted from with permission of Nature Publishing Group, Copyright 2015. ( G ) 3D printed instrumented cardiac microphysiological devices for on-line monitoring, reprinted from with permission of Nature Publishing Group, Copyright 2016.

Article Snippet: Compared with the previous biomimetic microsystems which were not well suitable for higher-throughput or longer-term studies [ , ], the novel system of 3D printed instrumented cardiac microphysiological devices would drastically simplify data acquisition and leverage the ability to track the temporal development in tissue mechanics, enabling new insights into tissue development and drug-induced structural and functional remodeling.

Techniques: Staining, Construct, On-line Monitoring

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: 3D printing sequence of the first perfusion fluidic device with an embedded 5 μm pore size cellular acetate membrane depicted in Fig. 2(b). (a) The bottom open serpentine channel was first 3D printed. (b) The cellular acetate membrane was then glued down on top of the bottom open serpentine channel. (c) 3D printing resumed after gluing down the cellular acetate membrane. (d) 3D printing completed with the cellular acetate membrane embedded between the top and the bottom open serpentine channels. Serpentine channel cross-sectional dimensions were 1 mm × 1 mm.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques: Sequencing, Pore Size, Membrane

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: Fluid perfusion flow experiment for testing the first 3D printed perfusion fluidic device with the embedded 5 μm pore size cellular acetate membrane depicted in Fig. 3(d). (a) Device priming with water flowing inside the top serpentine channel. (b) A blue colored food dye solution was flowing inside the bottom serpentine channel and diffusing through the cellular acetate membrane and into the top serpentine channel. The black and blue arrows indicate the flow direction. Flow rates were 100 μl/min.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques: Pore Size, Membrane

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: (a) 3D CAD model of the second perfusion fluidic device without the porous membrane, and the top and the bottom circular glass cover slips. (b) Schematic diagram of the exploded cross-sectional view of Section A–A depicted in (a) with the porous membrane separating the top and the bottom circular chambers. The top and the bottom circular glass cover slips were used as the top and the bottom surfaces of the top and the bottom circular chambers, respectively. (c) Second 3D printed perfusion fluidic device with the embedded 1.2 μm pore size cellular acetate membrane separating the top and the bottom circular chambers, and the integrated top and bottom circular glass cover slips. Channel cross-sectional dimensions were 1 mm × 1 mm and the two circular chambers were both 1 mm tall and 13 mm in diameter.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques: Membrane, Pore Size

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: Fluid perfusion experiment for testing the second 3D printed perfusion fluidic device with the embedded 1.2 μm pore size cellular acetate membrane separating the top and the bottom circular chambers, and the integrated top and bottom 15 mm diameter no. 1 circular glass cover slips depicted in Fig. 5(c). (a) Top and (b) bottom views of the device after water were pipetted inside the top and the bottom circular chambers. (c) Top and (d) bottom views of the device after a blue colored food dye solution was pipetted inside the bottom circular chamber. The blue colored food dye solution was gradually diffusing through the cellular acetate membrane and into the top circular chamber from the bottom circular chamber.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques: Pore Size, Membrane

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: (a) 3D CAD model of the third fluidic device without the top and the bottom circular polystyrene films. (b) Schematic diagram of the exploded cross-sectional view of Section A–A depicted in (a) with the top and the bottom circular polystyrene films. (c) Third 3D printed fluidic device with the integrated top and bottom 15 mm diameter 3 mil (∼75 μm) thick polystyrene films creating a circular chamber between them. (d) A blue colored food dye solution was pipetted inside the circular chamber. Channel cross-sectional dimensions were 1 mm × 1 mm and the circular chamber was 2 mm tall and 13 mm in diameter.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques:

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: (a) 3D CAD model of the fourth fluidic device without the top and the bottom rectangular glass cover slips. (b) Schematic diagram of the exploded cross-sectional view of Section A–A depicted in (a) with the top and the bottom rectangular glass cover slips. (c) 3D printed fluidic device with the integrated top and bottom 24 mm × 60 mm no.1 rectangular glass cover slips. (d) A blue colored food dye solution was pipetted inside the serpentine channel. Serpentine cross-sectional dimensions were 1 mm wide × 2 mm tall.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques:

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: (a) 3D CAD model of a serpentine channel mold without the bottom rectangular glass slide. (b) Schematic diagram of the exploded cross-sectional view of Section A–A depicted in (a) with the bottom rectangular glass slide. (c) 3D printed serpentine channel mold with the integrated bottom 75 mm × 50 mm and 0.96 mm to 1.06 mm thick rectangular glass slide. The cross-sectional dimensions of the serpentine structure were 1 mm × 1 mm.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques:

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: (a) 3D CAD model of the first optical device without the fiber. (b) Schematic diagram of the exploded cross-sectional view of Section A–A depicted in (a) with the fiber. The first 3D printed optical device with embedded Corning® Fibrance™ Light-Diffusing Fiber (c) was not and (d) was lit up using a green laser pointer.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques:

Journal: Biomicrofluidics

Article Title: Embedding objects during 3D printing to add new functionalities

doi: 10.1063/1.4958909

Figure Lengend Snippet: (a) 3D CAD model of the second optical device without the fiber, and the top and the bottom rectangular glass slides. (b) Schematic diagram of the exploded cross-sectional view of Section A–A depicted in (a) with the fiber, and the top and the bottom rectangular glass slides. (c) The second 3D printed optical device with embedded Corning® Fibrance™ Light-Diffusing Fiber, and the integrated top and bottom 75 mm × 50 mm and 0.96 mm to 1.06 mm thick rectangular glass slides. (d) The device was lit up using a green laser pointer.

Article Snippet: Finally, two 3D printed optical devices were demonstrated by embedding the Corning ® FibranceTM Light-Diffusing Fiber into the devices during 3D printing (Figs. and ).

Techniques: